A hormone is a chemical substance secreted by one tissue and travels by way of body fluids to affect another tissue in the body. Hence, it plays the role of a “chemical messenger.”
The pituitary is the master endocrine gland that secretes a large number of important hormones involved in the control of many bodily functions of both sexes. It releases a number of hormones for other endocrine glands, which then are picked up in the bloodstream. Each particular gland responds normally by producing its own hormone and discharges back into the bloodstream.
The amount and levels of hormones change daily. The sex hormones, estrogen and testosterone are produced in different quantities for men and women, in short bursts of minutes or hourly basis. The amount can vary between night and day and especially in different stage of a woman’s menstrual cycle and that explains why they are more under the influence of their hormones.
Estrogens are a group of steroid compounds, functioning as the main female sex hormone. They are produced primarily by developing egg follicles in the ovaries and the placenta – ready for the reproductive process.
Physical characteristics displayed include breasts, a widened pelvis, high body fat in the buttock, thigh and hip region. Other features are less facial hair and smoother skin than men.
As for men, the testis has a dual function of producing sperm and the hormone, testosterone. Their estrogen levels are generally low but tend to increase whilst testosterone levels decrease with increasing age. This hormonal imbalance can lead to prostate problems and exhibition of some women’s physical attributes.
Basically estrogen works by binding to and activating estrogen receptors which in turn allows the expression of many genes. As such, it is frequently used as part of some oral contraceptives, in estrogen replacement therapy for post-menopausal women, and in hormone replacement therapy for trans women.
Why do estrogen levels fall?
There are many reasons why estrogen levels fall, including:
- Hypogonadism (sex glands produce little or no hormones)
- Hypopituitarism (pituitary glands produce little or no hormones)
- Pregnancy failure
- Surgical removal - decline can happen abruptly in younger women whose ovaries are removed, resulting in a surgical menopause
- Menopause – suffer uncomfortable symptoms like hot flashes, night sweats, dryness or itching in the vagina, loss of libido, weak bones
- Polycystic ovarian syndrome – an endocrine condition that at time is seen in women of childbearing age who have difficulty getting pregnant
- Eating disorder – may experience a cessation of menstruation
- Extreme exercise or training – women with low body fat often do not produce sufficient amounts of sex hormones
- Women immediately after childbirth and also during breastfeeding
Why do estrogen levels rise?
+ During puberty, it is natural for estrogen levels to rise. This hormonal change results in developing breasts, better shape, fuller hips, pubic and underarm hair.
+ Estrogen levels rise during a healthy pregnancy
+ On the wrong side, high levels of estrogen are observed in women:
- who are obese
- with high blood pressure or diabetes
- with tumors of the ovaries, testes or adrenal glands.
- on drugs, such as steroid medications, ampicillin, estrogen-containing drugs, phenothiazines and tetracyclines
+ Isoflavones present in soy can cause a surge in estrogen known to protect cells against free radical oxidative damage. There are reported cases of young women who took high amount of soy products continuously for prolonged periods and developed cancer of the thyroid, breast and womb. However, for menopausal or postmenopausal women, soy is beneficial as it produces phytoestrogens which are good substitute for body’s own estrogen.
Points to note -
+ In cases of menstrual cycles being out of order, medical practitioners are fond of prescribing birth control pills. For some users, it can cause painful periods, weight-gain, depression, hot flashes, difficulty in movement etc.
+ On prolonged use, estrogen drug increases the risk of developing endometrial cancer (cancer of the uterus lining) or gallbladder disease that may need to be treated with surgery. To overcome this problem another medication – progestin is prescribed but can worsen the situation resulting in an increase in the risk of breast cancer, heart attack, stroke, blood clot in the lungs/legs and dementia. It is advisable to take estrogen only when necessary and go for the lowest dose that controls your symptoms.
Source: http://women.webmd.com/normal-testosterone-and-estrogen-levels-in-women
More comments
+ Study showed that an undernourished female body is linked to a deficit in estrogen metabolism and thus cannot neutralise the hormone completely, giving rise to abnormal cell growth. It has been discovered that indoles abundantly present in cruciferous vegetables (especially broccoli) activate certain protective enzymes to help in eliminating certain toxins such as ‘bad’ forms of the estrogen.
+ As liver breaks down estrogen and other hormones after they have performed their needed functions, keeping it healthy at all times is of paramount importance.
+ As compared to synthetic estrogens, the natural ones are safe and effective. They can be derived from plants like dong quai, fennel, fenugreek, ginseng, licorice, primrose oil, red clover and wild yam.
+ Estrogen receptor-positive (ER-positive) breast cancer is the most common type of breast cancer diagnosed today. According to the American Cancer Society, about 2 out of every 3 cases of breast cancer are hormone receptor-positive. Most of these cases are ER-positive, meaning that there are estrogen receptors on the surface of the cell that bind to estrogen.
By having ER-positive breast cancer, cancer cells grow in the presence of the hormone estrogen which occurs naturally in the body. Thus, drugs that interfere with estrogen’s ability to promote cancer cell growth can be used to treat ER-positive breast cancers.
VIVA corner
VIVA Life Science has formulated a product VIVA FEM to help women cope with stress, maintain a normal hormonal balance, relieve premenstrual syndrome, minimise menopause symptoms and other related women’s health problems. It contains natural ingredients as follows -
* Royal Jelly - revives the endocrine system and energises a weakened constitution
* Evening Primrose Oil – contains gamma-linolenic acid (GLA) that easily converts into prostaglandins which is helpful in supporting overall health
* Soy powder – protects cells against free radical damage and boosts levels of the body’s own antioxidants
* Wheat germ powder – alleviates problems like hot flushes, premature aging, breast tenderness
* Black cohosh root extract – helps relax muscles, relieves hot flashes, regulates menstrual flow, reduces fatigue, mood swings and night sweats
* Dong quai extract – relaxes uterine muscles, promotes calmness, strengthens reproductive system
* Vitamin B – increases energy, reduces irritability and calms PMS symptoms
* Raspberry leaf powder – relaxes and strengthens the uterus and normalises hormone levels
* Blueberry powder – strengthens collagen and supports neurological health
The menstrual cycle is the monthly series of changes a woman's body undergoes in preparation for the possibility of pregnancies. It involves the main female sex hormone - estrogens to develop egg follicles in the ovaries and the placenta termed 'ovulation'.
Another important sex hormone, progesterone is produced mainly to thicken the lining of the uterus in preparation for a fertilized egg.
- If an egg is implanted successfully in the uterine wall, progesterone helps to maintain the uterine lining throughout pregnancy and breastfeeding later. However, if the progesterone level is too low, the uterus may not be able to carry the fetus to term and can result in danger of miscarriage or death.
- If there is no fertilized egg, progesterone levels drop again and the lining of the uterus sheds through the vagina, resulting in a menstrual period. In the case of a woman with low progesterone, problems may arise such as abnormal uterine bleeding, irregular or absent periods.
Without progesterone to complement it, estrogen may become the dominant hormone. This may lead to a variety of symptoms, including:
Duration of cycle
The menstrual cycle varies from one individual to another but most experience longer cycles in the early years and shorten with increasing age. Menstrual flow may occur every 21 to 35 days and last 2 to 7 days. It can happen regularly or with some hiccups on irregular basis like period light/heavy and painful/painless and yet considered normal.
To find out what is normal for you, start keeping a record of your menstrual cycle. Begin by tracking your start date every month for several months in a row to identify the regularity of your periods. If you are having problems or you are concerned about the timing, flow or discomfort of your periods, then also make note of the following every month:
· End date. How long does your period typically last? Is it longer or shorter than usual?
· Flow. Record the heaviness of your flow. Does it seem lighter or heavier than usual? How often do you need new sanitary protection?
· Pain. Describe any pain associated with your period. Does the pain feel worse than usual?
Menstrual cycle irregularities can have many different causes, including:
· Pregnancy or breast-feeding. A delayed or missed period can be an early sign of pregnancy. If you have not had your period in six weeks and you have been sexually active, take a pregnancy test. Breast-feeding typically delays the return of menstruation following pregnancy.
· Eating disorders, extreme weight loss or excessive exercising. Eating disorders eg. anorexia nervosa, extreme weight loss and increased physical activity can disrupt menstruation.
· Polycystic ovary syndrome (PCOS). This common hormonal disorder may cause small cysts or fluid-filled sacs or pockets to develop in the ovaries along with irregular periods.
· Premature ovarian failure. It refers to the loss of normal ovarian function before age 40. Women who have this problem may not have periods or may get them irregularly.
· Endometriosis. This disorder causes tissue that normally lines the inside of your uterus to grow outside your uterus. It can cause some or severe pain during your period.
· Pelvic inflammatory disease (PID). This infection of the reproductive organs may cause irregular menstrual bleeding.
· Uterine fibroids. These are noncancerous growths of the uterus and may cause heavy menstrual periods and bleeding between periods.
For some women, use of birth control pills can help regulate menstrual cycles. However, some menstrual irregularities cannot be prevented. Regular pelvic exams can help ensure that problems affecting your reproductive organs are diagnosed as soon as possible.
In addition, consult your health care provider if:
· Your periods suddenly stop for more than 90 days
· Your periods become erratic after having been regular
· You bleed for more than seven days
· You bleed more heavily than usual — soaking through more than one pad or tampon every hour or two
· Your periods are less than 21 days or more than 35 days apart
· You bleed between periods
· You develop severe pain during your period
· You suddenly get a fever and feel sick after using tampons
Source: http://www.mayoclinic.com/health/menstrual-cycle
Recommendations
Up to 80% of women are known to struggle with premenstrual syndrome and its uncomfortable symptoms, report Yale researchers. This is because their nervous systems are sensitive to the ups and downs in estrogen and progesterone that occur naturally every month.
Studies showed snacking on 2 cups of yogurt a day can slash these symptoms by 48%, say researchers at New York's Columbia University. "Yogurt is rich in calcium, a mineral that naturally calms the nervous system, preventing painful symptoms even when hormones are in flux," explains Mary Jane Minkin, M.D., a professor of gynecology at Yale University.
Magnesium is another important mineral which acts as ‘nature’s tranquilliser’ to cope with menopausal symptoms such as anxiety, irritability and other mood changes.
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