Showing posts with label Alzheimer"s disease. Show all posts
Showing posts with label Alzheimer"s disease. Show all posts

Tuesday, 27 December 2016

Who am I ? - Alzhemier's

What is Alzheimer's disease?




Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive or behavioral decline. A neurodegenerative type of dementia, the disease starts mild and gets progressively worse.


Basically the total brain size shrinks with fewer nerve cells and connections.


Nerve fibers surrounding the hippocampus - the brain's memory center, become entangled and information is no longer carried properly to or from the brain. As such, new memories cannot be formed and old memories cannot be retrieved.






As more neurons die, additional parts of the brain are affected, and they begin to shrink. By the final stage of Alzheimer’s, damage is widespread, and brain tissue has shrunk significantly.

Causes


Dr. Alois Alzheimer who first identified the disease in 1906 found plaques which are numerous tiny, dense protein deposits known as beta-amyloid scattered throughout the brain that become toxic to brain cells at excessive levels. Brain cells depend on an internal support and transport system to carry nutrients and other essential materials throughout their long extensions. The tangles are within the brain neurons - from a disintegration of another protein, called tau. In Alzheimer's, threads of tau protein twist into abnormal tangles inside brain cells, leading to failure of the transport system.


In a nutshell, abnormal deposits of proteins form amyloid plaques and tau tangles throughout the brain, and once-healthy neurons stop functioning, lose connections with other neurons and eventually die.


Symptoms


As Alzheimer's accounts for between 60% and 80% of all cases of dementia, doctors have to be satisfied that there are symptoms of dementia present.


Observations involved cognitive or behavioral symptoms that show a decline from previous levels of "functioning and performing" and interfere with ability "to function at work or at usual activities. Also, symptoms of memory loss, especially in the area of learning and recalling new information.


Typical early symptoms of Alzheimer’s may include:
  • Regularly forgetting recent events or appointments, names and faces.
  • Repetitive questions or conversations after a very short interval.
  • Misplacing personal belongings or putting them in odd places.
  • Uncertainty about the date or time of day.
  • Getting lost on a familiar route or becoming unsure of their whereabouts or getting lost, particularly in unusual surroundings.
  • Impaired speaking, reading and writing.
  • Becoming low in mood, anxious or irritable, losing self-confidence or showing less interest in favorite activities.


As the disease progresses, the patient may have reactions that seem out of character like compulsive, obsessive, temperamental or socially unacceptable behavior. Some common reactions include repeating the same action or words, hiding possessions, physical outbursts and restlessness.


It can deteriorate further to affect a person’s coordination and mobility, to the point of inability to perform day-to-day tasks such as eating, bathing and getting dressed. Some do experience incontinence and neglect personal hygiene completely.


Finally, the most prominent deficits in "executive dysfunction" would be to do with reasoning, judgment and problem-solving. The person feels severely confused, disoriented and even hallucinated.  No longer can one intend or control the behavior with the resultant change in the brain structure. As a result, there may be total dependence on others for basic care. In the worst scenario, the person may be bedridden as the body shuts down.


Risk factors


(1)  Controllable factors


Some evidence suggests that the same factors that put you at risk of heart disease also may increase the chance that you will develop Alzheimer's. Examples include:
  • Lack of exercise
  • Obesity
  • Smoking or exposure to secondhand smoke
  • High blood pressure
  • High blood cholesterol
  • Poorly controlled type 2 diabetes
  • A diet lacking in fruits and vegetables
Late-onset Alzheimer's arises from a complex series of brain changes that occur over decades. The causes probably include a combination of genetic, environmental and lifestyle factors (enumerated above). The importance of any one of these factors in increasing or decreasing the risk of developing Alzheimer’s may differ from person to person.



(2)  Uncontrollable factors


People with early-onset Alzheimer's represent less than 5% of all sufferers with genetic mutation being the usual cause. Having Alzheimer's runs in the family is associated with higher risk which may manifest around 30-60 years of age. Having a certain gene (the apolipoprotein E or APOE gene) puts a person, depending on their specific genetics, at 3-8 times more risk than a person without the gene.


Other contributory factors include:


  • Age - though not a normal part of aging, it afflicts 10% of the general population over 65 and as many as 50% over 85.
  • Prior head injury - mostly tie to the severity of trauma history.
  • Sleep disorders (eg. the breathing problem sleep apnea).
  • Low educational and occupational attainment.
  • Down syndrome -  signs and symptoms of Alzheimer's tend to appear 10 to 20 years earlier in people with Down syndrome than the general population because they have an extra copy of chromosome 21, which contains the gene that generates harmful amyloid.


  • Precautions/prevention


    There is no known cure for Alzheimer's disease - the death of brain cells in the dementia cannot be halted or reversed. Research has some interesting findings which call for modification of lifestyle to reduce the occurrence or severity of the disease:


    (1)  Most sufferers are found lacking in nutrition due to unbalanced diet, consuming too much processed foods and drug medication. For example:
    -  Vitamin B range are vital in cognitive functioning.   
    -  Antioxidants like Vitamin A, C and E are crucial in clearing free radicals which can attack the brain cells.
    -  Minerals such as boron, potassium and selenium are important in preserving cell integrity.


    (2)  Autopsies of patients who have died of Alzheimer's reveal excessive amounts of aluminum in their hippocampus area and in the cerebral cortex -the external area of grey matter responsible for higher brain functions eg. abstract thinking, judgment, memory and language.


    (3)  Another toxic metal that can penetrate the blood barrier encapsulating the brain is mercury. For most people, the release of mercury from dental amalgams is the primary means of this exposure.


    (4)  Powerful immune system proteins called complement proteins have been found around the plaques and tangles in the brains of patients dying from Alzheimer's. Some experts theorize that such proteins normally help to clear away dead or degenerating cells which in turn produce amyloid. Unfortunately, the immune system attacks the healthy cells as well resulting in a critical mass accumulating in the brain.


    Recommendations


    The Alzheimer's Association recommends important some elements of dementia care:
    • Effective management of any conditions occurring alongside the Alzheimer's.
    • Activities and/or programs of adult day care - A new study, published in the Journal of Alzheimer's Disease, finds that any kind of exercise can improve brain volume and cut the risk of Alzheimer's disease by 50%.
    • Support groups and services.
    A nutritious diet, physical activity, social engagement and mentally stimulating pursuits have all been associated with helping people stay healthy as they age. These factors might also help reduce the risk of cognitive decline and Alzheimer’s disease.


    Though aging is a natural process, we do not have to end up suffering from Alzhemier's!


    Viva corner





    Viva Oxypower contains coenzyme10 which helps to increase oxygenation of cells and is involved in the generation of cellular energy. B-easy with its folic acid content to aid in controlling homocysteine levels and B12 content to boost memory and cognitive functions.


    People with Alzheimer's tend to have a shortage of some vital chemical messengers
    which are responsible for transmitting signals around the brain. Viva Biolecthin with choline can assist to improve nerve communication.





    Chloroguard is an well-rounded product that provides a whole range of vitamins, aminos, fiber and minerals. Its Omega3 content provides the essential DHA for proper brain functioning. It is also a blood cleanser agent that can remove heavy metals from obstructing circulation. Viva Ageguard provides the amino acids for the formation of regenerative tissue.





    Liquick gingko helps to improve blood circulation in the capillaries lying the brain so that more oxygen can be delivered before more brain cells are suffocated. The grape seed extract in Cellpex is a potent antioxidant that readily passes the blood brain barrier to protect brain cells from radical damage.





    Lost in time - dementia

     


    Senility is defined as the weakness or mental infirmity of old age, and is associated with the deterioration of the body and mind in the elderly (usually defined in this context as over 65 years of age). It is commonly referred to as dementia.

    Different areas of the brain control different skills and abilities. When mental functions such as memory, language, orientation or judgment deteriorate, this may be a direct result of the way dementia has affected the brain. In simple terms, it refers to a loss of brain cells to a point where mental disability results.

    Causes

    There are various diseases associated with senility though not all of them are directly associated with advanced age and can occur in children and babies.

    These degenerative brain diseases include:
    • Alzheimer’s Disease
    • Parkinson’s Disease
    • Vascular Dementia
    • Huntington’s Chorea
    • Creutzfeldt-Jakob
    • Lewy Body Disease
    Alzheimer’s disease is the most common form of senility, where people experience extreme forgetfulness such as difficulty remembering past events (especially the more recent ones) as well as learning new things. Damage to the brain begins years before symptoms appear. Abnormal protein deposits form plaques and tangles in the brain of someone with Alzheimer’s disease. Connections between cells are lost, and begin to die. In advanced cases, the brain shows significant shrinkage.

    Other causes of senility include:
    • Drug addiction
    • Anxiety
    • Depression
    • Stroke
    • Poor nutrition
    • Thyroid dysfunction (e.g. Hashimoto’s Disease)
    • Alcoholism
    • Constant lack of sleep
    A recent study conducted found people in their 30s and 40s who are constantly lacking sleep could find themselves with dementia by their 60s.  This is because in our slumber the brain is clearing the protein wastes (beta amyloid) that develop when it processes the energy required. The rate of clearance is estimated to be 6 times during this time as compared to awakening hours.  Failure to reduce this accumulated pile can result in brain damage in the years to come.
    Other less common conditions which may accompany senility include:
    • Urinary Tract Infection
    • Multiple Sclerosis
    • Wilson’s Disease
    • Amyotrophic Lateral Sclerosis
    • Brain Tumor
    • AIDS Dementia

    Diagnose


    Properly diagnosing degenerative brain diseases like senility requires a professional screening and/or evaluation by a healthcare practitioner. An accurate assessment is after 6 months of signs and symptoms present observed by the sufferer or close family and friends. In all types of general cognitive dysfunction, higher mental functions are affected first in the process.

    Signs & Symptoms



    Senility is caused by the degeneration of the brain cells. As a result, senility symptoms can include:
    • Progressive memory loss
    • Anorexi
    • Poor judgment
    • Impaired concentration
    • Confusion
    Often, noticeable personality changes are signs of senility.

    Symptoms of dementia can be classified as either reversible or irreversible, depending upon the etiology of the disease. Less than 10% of cases of dementia are due to causes that may presently be reversed with treatment. Causes include many different specific disease processes, in the same way that symptoms of organ dysfunction such as shortness of breath, jaundice, or pain are attributable to many etiologies.

    Pain

    As people age, they experience more health problems, which mostly carry a substantial burden of pain. Statistics put between 25% and 50% of older adults experiencing persistent pain. Seniors with dementia experience the same prevalence of conditions likely to cause pain as seniors without dementia. Pain is often overlooked in older adults and, when screened for, often poorly assessed, especially among those with dementia. Beyond the issue of humane care, unrelieved pain has functional implications. Persistent pain can lead to decreased ambulation, depressed mood, sleep disturbances, impaired appetite and exacerbation of cognitive impairment, and pain-related interference with activity is a factor contributing to falls in the elderly.

    Help needed

    + Generally, because it is a degenerative condition, individuals suffering from senility become progressively worse with time. Especially in the later stages of the condition, affected persons may be disoriented in time (not knowing what day of the week, day of the month, or even what year it is), in place (not knowing where they are), and in person (not knowing who they are or others around them).

    + Additional mental and behavioral problems often affect people who have dementia, and may influence quality of life, caregivers and the need for institutionalization. As dementia worsens individuals may neglect themselves and may become disinhibited and incontinent as their condition worsens. Dementia, though often treatable to some degree, is usually due to causes that are progressive and incurable.

    + Even for incurable cases, early recognition can allow you to create a management plan that will ensure the greatest quality of life for the greatest amount of time, while lessening common senility symptoms. A thorough examination and accurate diagnosis is necessary to create a successful management plan.

    + Adult daycare centers as well as special care units in nursing homes often provide specialized care for dementia patients. Adult daycare centers offer supervision, recreation, meals and limited health care to participants, as well as providing respite for caregivers.

    + While some preliminary studies have found that music therapy may be useful in helping patients with dementia, their quality has been low and no reliable conclusions can be drawn from them.

    + Medications can be prescribed to slow the progress of senility and other degenerative brain diseases, but success is often coupled with unwanted side effects, particularly in the elderly patient. In any case, medication should be used in conjunction with psychiatric or behavioral therapies.

    + Unlike prescription medications, alternative therapies like natural remedies are virtually free of these unwanted side effects, and are a welcome treatment option for managing senility symptoms. They also work well in combination with psychiatric or behavioral therapies.

    + Additionally, proper nutrition, exercise, and positive lifestyle choices are important in sustaining mental clarity. As we grow older, it is important to participate in stimulating activities, thus keeping our minds active, this is especially true for the elderly.

    + To be healthy in late life, a rich accumulation of life experiences – education, marriage, socializing, a stimulating job, language skills, having a purpose in life, physical activity and mentally demanding leisure activities help to keep the brain going. One can even have significant Alzheimer’s pathology and no symptoms of dementia due to such high cognitive reserve, says David Bennett, M.D., of Chicago’s Rush University Medical Center.
     
    Hence, do not neglect the importance of social interaction, good friends and family relationships to enjoy a fruitful ripe age.

    Source: http://www.nativeremedies.com/ailment/senility-degenerative-brain-diseases-info.html
    http://en.wikipedia.org/wiki/Dementia

    Nutritional benefits

    + A combination of herbal and homeopathic remedies such as Ginkgo biloba, Hawthorn, Rosemary and American Ginseng provide safe, effective relief and support the brain and mental health.

    + Vitamin deficiencies and chronic infections may occur at any age, with symptoms manifesting before dementia occurs. Hence, routine blood tests can be performed to rule out treatable causes when an elderly is suspected of abnormalities like confusion or disorientation.

    + Degenerative dementia can be due to deficiencies of vitamin12, folate or niacin (all found in the Vitamin B family). High levels of the amino acid homocysteine are linked to brain shrinkage and an increased risk of Alzheimer's and B vitamins are known to suppress it. In a study conducted among participants taking high doses of folic acid and vitamins B6 and B12, blood levels of homocysteine were lowered as was the associated brain shrinkage – by up to 90%!


    +  A “severe deficiency” of vitamin D boosts older Americans’ risk of cognitive impairment 400%, an alarming study by England’s University of Exeter finds. Experts recommend a daily dose of 800 IU to 2,000 IU of vitamin D3.  Researchers believe that optimal vitamin D levels may enhance the amount of important chemicals in your brain and protect brain cells by increasing the effectiveness of the glial cells in nursing damaged neurons back to health.

    VIVA corner



    +  Ageguard and Royal Jelly increases and balances hormones respectively and thus retards aging.


    +  Biolecithin improves neuro transmission of messages with its protective mechanism on the myelin sheath covering the neurons.



    +  Dailyguard provides a host of nutrients to feed the cells for healthy growth.

    +  High intake of the omega-3 fats EPA and DHA is essential for preserving the brain cells and eliminates any inflammation, thereby slowing down its progression and lowering your risk of developing brain disorder.

    .